Ok so theres a couple of things here to be aware of:
Products like Epix or any other pixel tape is distinctly different to other led tape in that the pixel tape types have a tiny little chip in them that can recieve dmx data (typically over artnet) I call these tape types addressable. On the other hand, non addressable led tape recieves no dmx data, its just recieving voltage.
In order to work out how much tape you can run off any given decoder is going to involve some maths. For example, the enntec cvc4 is 20 amps split over 4 channels gives you 5 amps per channel. So you’ll need to work out what the amps per metre rating of whatever tape you use is rated at, AND also calculate the voltage drop over the distance of cabeling + tape. For safety reasons, i would advise installing in line fuses per channel rated at 5amps each, And once fully built getting it pat tested.
Running strips in series is entirely possible, but you need to be very aware of how many amps your cables can handle, and how many amps are able to pass through the strips. If you get the maths wrong, the first strip or cable in the series will be the first to melt. (which is why i suggest inline fuse.)
I once built a 32 channel led tape system, each channel was operating a 1m tape of just solid white smd 5050. The wiring was an absolute knightmare, soldering onto all the connector blocks was a pain in the ass, the points on the tape for the connector blocks are not very robust so you’ll be lucky to get a couple of gigs out of it, the cost soon added up quickly with all the cabelling, inline fuses, connector clips, tape, circuit board.
Personally, if you are dead set on the opz for control, and your happy with rgbw as one pixel per fixture, i would reccomend taking a look at some of the dmx led bars on offer. Will last a lot longer and therefore more cost effective in the long run, easier and quicker to rig, easier to pat test, and safer.
If it were me, i’d be looking at some of the laser tilt bars in red which look super cool and are less than 500mw per beam (safe for crowd scan). Led tapes and bars have been done over and over. . Even though the opz is not designed to do pan and tilt i.e movements, you can still patch a generic dimmer for the tilt and sequence it.